SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
<P>The sirtuin family of nicotinamide adenine dinucleotide-dependant (NAD) deacetylases plays an important role in aging and metabolic regulation. In yeast, the Sir2 gene and its homolog Hst2 independently mediate the action of ca...
Disparities in Diabetes Care: Impact of Mental Illness
Abstract BACKGROUND: Emerging evidence indicates that patients with mental health conditions (MHCs) may receive less intensive medical care. Diabetes serves as a useful condition in which to test for MHC-related disparities in care. W...
Helicobacter pylori-induced gastric inflammation and gastric cancer
Helicobacter pylori (H. pylori) infect over half of the world’s population. The prevalence of H. pylori infection and the predominant genotype of H. pylori virulence factors vary considerably across different geographical regions. H...
Asymmetric Hydrophosphonylation of α-Ketoesters Catalyzed by Cinchona-Derived Thiourea Organocatalysts
Naturally catalytic: The cinchonidine- and cinchonine-derived bifunctional thiourea organocatalysts 1âa and 1âg (see picture) have been applied in the asymmetric hydrophosphonylation of aromatic and heteroaromatic -...
Modeling the isolated cardiac myocyte
http://linkinghub.elsevier.com/retrieve/pii/S0079610703001147
JL Puglisi
，
Fei Wang
，
Donald M. Bers
被引量:
208
A High Power Density Single-Phase PWM Rectifier With Active Ripple Energy Storage
It is well known that single-phase pulse width modulation rectifiers have second-order harmonic currents and corresponding ripple voltages on the dc bus. The low-frequency harmonic current is normally filtered using a bulk capacitor i...
Community discovery using nonnegative matrix factorization
http://link.springer.com/article/10.1007%2Fs10618-010-0181-y
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Transient plasma ignition of quiescent and flowing air/fuel mixtures
Transient plasmas that exist during the formative phase of a pulse-ignited atmospheric pressure discharge were studied for application to ignition of quiescent and flowing fuel-air mixtures. Quiescent methane-air mixture ignition was ...
Comparative analysis of proteome maps of silkworm hemolymph during different developmental stages
http://link.springer.com/article/10.1186%2F1477-5956-8-45
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HighâPerformance Solar Cells using a SolutionâProcessed Small Molecule Containing Benzodithiophene Unit
A conjugated small molecule containing a benzodithiophene unit shows high performance in bulk heterojunction (BHJ) solar cells. Using the simple solution spinning process, a high PCE is achieved by employing this molecule as the donor...